DOCTOR EXPLAINS
How nattokinase clears blocked arteries
An expert explains how nattokinase clears blocked arteries.
Clear arteries. No statin.🇮🇪 Made in IrelandFREE DELIVERY OVER €33PRICES IN € · VAT INCLUDED · NO CUSTOMS FEESLab measured 10,400 FU90,000+ customers90-day money-back guarantee
HOLTMORE · 8-IN-1 CARDIOVASCULAR FORMULA
10,000 FU NattokinaseMost Powerful Cardiovascular Protocol
1 / 16
Clear your arteries. No statin. No side effects.
- Dissolves the fibrin your plaque is built on.
- Shrinks old plaque — 36% in 12 months.
- Drops your blood pressure — top and bottom number.
- Drops your LDL. No statin.
- Clears clots before they block a pipe.
- Warm hands and feet again.
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Lab measured 10,400 FU. Most bottles hide 2,000.
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DOCTOR'S PICK
I tell my patients this. Most nattokinase is underdosed. This is the full 10,000 FU — the dose the studies used. I recommend it for the heart.— Dr Alan Reeves, MD
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NATTOKINASE LAB TEST ✓ PASS
Label: 10,000 FU. Lab measured: 10,400 FU.
An outside lab tested our batch. We publish the lab report.
Lab Verified Results
Supplement Facts & Ingredients
- One serving = 1 vegetarian capsule. 90 capsules per bottle.
- Nattokinase 500 mg (10,000 FU)
- Heart blend 500 mg: CoQ10, turmeric root, dandelion root, aged garlic, grape seed
- Bromelain 10 mg (2,400 GDU/g)
- Pine bark 5 mg
- 8 ingredients. One capsule. Third-party lab tested. Non-GMO. No soy.
How to use
One capsule a day. That's the full dose. Take it with water, same time every day. Keep the bottle next to the kettle. Missed a day? Just take one tomorrow.
Safe with my blood pressure or cholesterol tablets?
You start it next to your tablets. One capsule a day.
MADE IN IRELAND · LAB-TESTED · NON-GMO
Made In Ireland. Tested Every Batch.
🇮🇪 Made in IrelandLabel says 10,000 FU. The lab measured 10,400. Made in a cGMP facility. Every batch goes to an outside lab.
What Doctors Are Saying About Nattokinase
Don't just take our word for it. Watch the experts.
SPECIALIST
Nattokinase, clots and blood pressure
Same blood. Lower pressure. Clearer pipe.
THE DOSE
Why the dose matters
2,000 FU does nothing. 10,000 FU is the dose.
It's Not Your Fault.
Your GP had ten minutes. No one told you what really clogs your arteries.
Over 400,000 people in Ireland are on a statin. Almost none were told about fibrin.
You ate better. You walked more. The clog stayed.
Your statin freezes the plaque. It cuts your CoQ10 in half.
The real enemy has a name: fibrin. It's a sticky web in your blood. Plaque and clots stick to it. Your statin never touches it.
CoQ10 is the fuel your heart runs on. Less of it, and you feel tired and old.
There's a better way. One that goes after the fibrin — the real cause.
Your GP never said fibrin.
Plaque is built on fibrin. This breaks the fibrin down.
The full 10,000 FU. Not the weak 2,000 on the chemist shelf.
The cupboard you already tried. Atorvastatin. Simvastatin. Beetroot juice. Cod liver oil. 2,000 FU natto from the chemist. None of them break fibrin.
CLOGGED ARTERIES? THE PART NO ONE EXPLAINED
Plaque Is Built On Fibrin. So Break It Down.
- 01
Fibrin is the glue.
It's a sticky web in your blood. It traps fat and cells. It holds the clog together.
- 02
This enzyme breaks the glue.
Nattokinase breaks the fibrin web down. Less glue. Clearer pipes.
- 03
The clog loses its grip.
Blood flows easier. The pressure on your arteries drops.
WHY NOTHING HAS WORKED
You Tried Everything. None Of It Touches Fibrin.
You cut out the fry and the red meat.
✗ Why it failed: Diet slows new buildup. It can't dissolve the old web of fibrin.
Your GP put you on a statin.
✗ Why it failed: Your statin lowers a number. The plaque stays. It never touches the fibrin.
You bought cheap natto online.
✗ Why it failed: 2,000 FU did nothing. 3,600 FU did nothing. And most “10,000 FU” bottles on Amazon have no lab report. Cheap Chinese powder. A big number on the label. One lab found 711 FU in a bottle that promised 4,000.
Holtmore: label 10,000 FU. Lab measured 10,400 FU.
You tried beetroot juice.
✗ Why it failed: Beetroot juice opens the pipe for hours. The clog stays. It never touches the fibrin.
| Your symptom | The real cause |
|---|---|
| Chest feels tight on the stairs | Your heart pushes blood through a narrowing pipe. |
| Out of breath walking the dog | Less blood gets through. Your muscles starve for oxygen. |
| Cold, numb, tingling feet | Thick, sticky blood can't reach the far ends. |
| Calf pain when you walk | Clogged leg arteries. The same clog sits near your heart. |
| Blood pressure up, even on your tablets | Your tablets lower the push. The pipe stays narrow. |
| Calcium score came back high | Plaque has been building for years. Silently. |
| Brain fog. Losing words. | Sludgy blood. Less of it reaches your brain. |
| “Normal” LDL, bad scan | Your plaque sits on fibrin, not on your number. |
Every one of these starts with fibrin. So that's where Holtmore starts.
Fit? Lean? Clean Diet? Plaque Doesn't Care.
You run. You eat clean. You're not heavy. So you feel safe. But plaque builds quietly — no pain, no warning.
One runner did cardio for 35 years. Clean diet. His heart scan still came back dangerously high. A clean diet can't dissolve plaque that's already there.
You can't out-run a clog.
3 in 4 heart attacks had “normal” LDL. Half were under 2.6 mmol/L.
But you can break it down. Plaque is built on fibrin. Nattokinase dissolves fibrin. At the full 10,000 FU, not a weak 2,000.
Don't wait for your scan.
Why 10,000 FU Works When 2,000 FU Doesn't
Weak doses only keep healthy arteries healthy. They're too weak to break down the buildup choking yours. And statins just freeze what's already there.
| Holtmore 10,000 FU | Underdosed natto (2,000 FU) | Statins | |
|---|---|---|---|
| Dose | Full 10,000 FU. Lab: 10,400 | 2,000 FU. Too low to work | Not a dose |
| The plaque | Breaks down the fibrin under it | Too weak to help | Just freezes it in place |
| Plaque shrink in studies | 36% in 12 months | Low doses did nothing | 11.5% (natto: 36.6%) |
| CoQ10 | Adds it back | None | Drains it — about half in 30 days |
| Side effects | None reported | — | Muscle pain, brain fog |
| Guarantee | 90 days, every penny back | Varies | None |
You won't need a statin.
Mary O'B., 61, Limerick
★★★★★Cholesterol 6.8 down to 5.1. No statin.
My GP wanted me on a statin at my check-up. I asked for three months. Total cholesterol went from 6.8 to 5.1 mmol/L. He asked what I was taking.
Gary W., 67, Athlone
★★★★★My top number was 152. Now it's 128.
Same cuff. Same chair. Same time every morning. I wrote every reading down. It just kept dropping.
Tom R., 64, Kilkenny
★★★★★I'm a runner. My calcium score came back 383.
It scared me. Lean my whole life. Ate clean. This is the only thing I added. My rescan came back lower. My cardiologist asked what I changed.
Declan M., 62, Cork
★★★★★My heart scan score dropped. My GP went quiet.
Six years on a statin. Plaque just sat there. Twelve weeks on this and my feet are warm again. My GP asked what I'd changed.
Brendan K., 64, Waterford
★★★★★Dad went at 61. Not me.
My dad died of his heart at 61. I'm 64. My blood pressure crept up at every check-up. Eight weeks on this, it was down to 128/80. My GP said keep doing whatever you're doing.
1 / 5
Why not beetroot juice, fish oil or low-dose aspirin?
- Beetroot juice opens the pipe for hours.
- Fish oil never touches fibrin.
- Aspirin thins the blood. It never breaks the glue.
- This breaks the glue.
You won't need a statin.
Every day, around 25 people in Ireland die from heart disease or stroke.Irish Heart Foundation
1 in 5 heart attacks is silent. You never feel it.
10,000 FU — the full studied dose · 🇮🇪 Made in Ireland · cGMP facility · Third-party lab tested · Free delivery over €33
✓ LAB TESTED · PASS
Label 10,000 FU.
Lab 10,400 FU.
On the label10,000 FU
Measured by an outside lab10,400 FU
REASON 1
Lab Result: 10,400 FU
Label: 10,000 FU. An outside lab measured 10,400 FU per capsule. Read the report.
REASON 2
Nattokinase Breaks The Fibrin. CoQ10 Puts Back What Your Statin Stole.
- Nattokinase — 500 mg (10,000 FU): breaks the fibrin that clogs you.
- CoQ10: puts back what your statin stole.
- Aged garlic: goes after the plaque.
- Turmeric: calms the swelling behind the plaque.
- Bromelain (2,400 GDU/g): makes the enzymes work harder.
- Grape seed: backs up your blood vessel walls.
- Pine bark: keeps your blood moving.
- Dandelion root: flushes out extra fluid.
All 8 in one capsule. You don't have to build your own stack.
REASON 3
All The Power Of Natto. None Of The Slime.
Real natto is slimy. It smells strong. It's full of soy. And you never know how much enzyme is in the bowl. Holtmore gives you just the enzyme, measured in the lab. No smell. No taste. No soy.
What You'll Feel — Week By Week
Your arteries didn't clog in a week. They won't clear in one either. Here's the path most people walk on the full 10,000 FU.
WEEKS 1–2
The Enzyme Hits The Fibrin
It starts breaking down fibrin on day one. That's the sticky web clots are built on. Some people feel lighter right away. Most feel nothing big yet. That's normal. The work happens where you can't see it.
WEEKS 3–4
Warm Hands And Feet
Cold hands and feet warm up. Blood reaches the far corners again. Your pipes are getting cleaner. You start to feel it.
WEEKS 5–8
The Cuff Number Drops
This is where it counts. Your BP cuff shows lower numbers. Stairs get easier. Walks get longer. This is exactly where 2,000 FU pills stall out. At 10,000 FU, the enzyme keeps going.
WEEKS 9–12+
Your GP Asks What You Did
Get your next blood test. That's your proof. The big study ran 12 months. Plaque shrank 36%. Not stalled. Reversed. That's why you don't stop at one bottle.
Buy 2, Get 2
The Small Things Come Back First.
- Warm fingers on the mug.
- Stairs without the stop.
- Cold feet gone by the six o'clock news.
- The cuff goes on and your stomach doesn't drop.
- One bottle on the shelf instead of forty.
That's what an open artery feels like from the inside.
Then the big one arrives. Your numbers come back different. Your GP asks what you've been doing. You get to say you did it yourself.
Your clogged arteries will be gone. You won't need a statin to get there.
340+ PUBLISHED STUDIES ON NATTOKINASE
Real Studies. Real Numbers.
Plaque Shrank 36% In 12 Months. 1,062 People.
One full year. 10,800 FU a day. Plaque got 36% smaller. LDL dropped too.
Chen et al., 2022
3,600 FU Did Nothing. 10,000 FU Is This Capsule.
The same 12-month study tested 3,600 FU a day. Plaque didn't budge. Only the high dose worked.
Chen et al., 2022
3× More Plaque Drop Than A Statin. 36.6% vs 11.5%.
Head to head for 26 weeks. Nattokinase shrank plaque 36.6%. The statin shrank it 11.5%.
Ren et al., 2017
Most Pills Are Junk. These Numbers Are Not.
36%
less plaque. 1,062 people.
Chen 20223×
the plaque drop of a statin.
head to head · Ren 201777.7%
had thinner artery walls.
12-month study · Chen 202290,000+
already switched.
HoltmoreNot 2,000 FU. The full 10,000 FU — the dose that did the job.
90-day money-back guarantee
THE JAPANESE ENZYME
In 1980, a Japanese scientist, Dr Hiroyuki Sumi, put natto on a blood clot. In 18 hours, the clot was gone. Same enzyme. Full dose.
2,000 FU did nothing. 3,600 FU did nothing. This is 10,000 FU.
HOW THE DOSE STACKS UP
FU per capsule. The only number that matters.
6,000 FU — where plaque reversal starts
2,000 FU
4,000 FU
10,000 FU
most brands
even your own stack
HOLTMORE
Your Heart. Her Heart. Same Kitchen. Same Risk.
You eat the same food. You sit on the same sofa. Plaque doesn't pick just one of you. Buy 2, Get 2 gives you 4 bottles. Two hearts. One order.
4 bottles. 90 capsules each. €10.74 a bottle.
FREE delivery · 90-day money-back guarantee
90-DAY MONEY-BACK GUARANTEE
Better Numbers At Your Next Check-Up. Or Every Cent Back.
- 01
One capsule a day.
Every day, for up to 90 days.
- 02
Check the cuff. Then the blood test.
- 03
Numbers didn't move? Every cent back.
Email us at support@holtmore.com. No questions asked.
The only risk is doing nothing.
LAST CHANCE · SALE ENDS MIDNIGHT
Try It For 90 Days. Risk Nothing.
4 bottles. €42.95. 2 free. Free delivery. Free gift. Less than one GP visit.
The real risk is the plaque that keeps building.
Still Have Questions? Good.
Ask before you trust your heart to anything. Here are honest answers.
How does it actually work?
Plaque sits on fibrin. This breaks the fibrin down. Fibrin is a sticky web. It builds up inside your arteries. Nattokinase breaks that web down. It goes after the buildup itself. Some tablets only lower a number. They leave the buildup sitting there. As one doctor put it: “the car's in neutral.” This works on the root cause instead.
Can I take it with my blood pressure, cholesterol or blood-thinner tablets?
Nattokinase is a gentle, natural enzyme. The Japanese have eaten it in food for centuries. On a prescription blood thinner? Start with one capsule a day and listen to your body. You start it next to what you take now. Every batch is third-party tested, and you can see the COA any time.
Is this underdosed like every other brand?
2,000 FU did nothing. 3,600 FU did nothing. This is 10,000 FU. You get the full 10,000 FU in one capsule. Most brands give you 2,000 to 4,000 FU. At that level, you waste your money. The 12-month study tested 3,600 FU a day. It did nothing. The high dose shrank plaque 36%. One Holtmore capsule equals five 2,000 FU capsules.
I'm already on a statin. Why add this?
Your statin freezes the plaque. It never breaks the glue. It also cuts your CoQ10 in half in 30 days. You start this next to it. One capsule a day.
I already take 2,000 FU nattokinase. Isn't that enough?
That dose failed. The 12-month study tested 3,600 FU. Plaque did not move. You need 10,000 FU. This is one capsule, not five.
I take blood pressure tablets. How do I start?
You start it next to what you take now. One capsule a day. Same time. Every batch is lab tested. Label 10,000 FU. Lab 10,400 FU.
Is 10,000 FU just a number printed on the label?
Don't read the label. Read the lab. Label says 10,000 FU. The outside lab measured 10,400 FU. We publish the report.
When will I feel it?
Most people feel warmer hands and feet in 3–4 weeks. By weeks 5–8, stairs get easier. Your BP cuff shows lower numbers. Plaque and cholesterol change over months. Check them at your next blood test. You get 90 days to judge it.
Any side effects?
No side effects reported. No muscle pain. No brain fog. It's the same enzyme Japan has eaten in natto every day for 1,000 years. The capsule contains no soy. Every batch is third-party tested.
Why not Lumbrokinase or Serrapeptase instead?
Those are single enzymes on their own. This is a full clinical-dose stack. You get 10,000 FU nattokinase. You also get CoQ10, aged garlic, bromelain and pine bark. They are built to work together. One enzyme alone can't do that.
Will my stomach acid destroy it first?
Good question. The capsule is built to protect the enzyme. So it reaches your gut to work. cGMP facility. Third-party tested.
Can I just eat natto instead?
You can try. Natto is slimy and smells strong. Most people can't eat it every day. And you never know how much enzyme is in your bowl. One Holtmore capsule gives you a lab-tested 10,000 FU. No smell. No taste. No soy. No cooking.
Why 8-in-1 instead of plain nattokinase?
Nattokinase breaks down the fibrin. CoQ10 puts back what statins drain. Aged garlic goes after plaque. Turmeric calms the swelling. Bromelain makes the enzymes work harder. Grape seed and pine bark back up your vessel walls. Dandelion flushes out extra fluid. One capsule instead of eight bottles.
I already take a cupboard full of tablets. Why add one more?
Because this one can replace a few. Nattokinase, CoQ10, aged garlic, turmeric and more. All in one capsule. One bottle on the shelf instead of forty.
How do refills work?
Your first order goes out right away. Then one bottle is sent every 28 days for €40.95. Skip a month or cancel any time. Just email support@holtmore.com. Or tap “Manage Subscription” at the bottom of this page. No calls. No hoops.
How much is delivery, and how fast is it?
Delivery is FREE on orders over €33. So the 4-bottle deal comes free. Under that, it's just €2.25. It's made in Ireland and goes out with An Post, tracked. Prices are in euro with VAT included. No customs fees. No Brexit charges. Your order ships out within 1–2 working days, with tracking.
Where do you deliver? Where is it made?
We deliver to Ireland, the UK, the USA, Canada, Australia and New Zealand. Your Holtmore is made in Ireland and sent from Ireland. Every batch is third-party lab tested.
Does it contain soy or vitamin K2?
No. The capsule contains no soy. No added vitamin K2. Nothing to second-guess next to your meds. Non-GMO.
How do I take it?
One capsule a day with water. Same time every day. That's the full 10,000 FU. Tip: keep the bottle next to the kettle.
Too expensive? What if it doesn't work for me?
4 bottles are €42.95. Take it 90 days. Numbers don't move? Every cent back. The only risk is doing nothing. Just email support@holtmore.com. No questions asked.
Customer Reviews
Verified reviews from people 50+ — every story of taking back their heart.